Index - 28 - 29 - 30/31 - 32/33/34 - 35 - 36/37/38/39 - 40/41 - 42/43 - 44/45/46 - 47/48 - 49 - 50/51/52/53
54/55 - 56 - 57/58 - 59 - 60/61 - 62 - Pages online: A - B - C - D - E - F - G - References
DOSE ADJUSTMENT OF ANTIRETROVIRALS FOR IMPAIRED RENAL FUNCTION
eGFR i (ml/min) hemodialysis
≥50 30-49 10-29 <10
ddI EC ii
≥60kg
<60kg

 
400mg q24h
250mg q24h

 
200mg q24h
125mg q24h

 
125mg q24h
125mg q24h

do not use
FTC
200mg		 q24h q48h q72h q96h q96h
TDF
300mg		 q24h q48h q72-96h no data q7d AD iv
FTC/TDF q24h q48h use individual drugs
3TC 300mg q24h 150mg q24h 100mg q24h iii 50-25mg q24h iii 25mg q24h iii AD iv
ZDV
300mg		 q12h q12h q12h 100mg q8h 100mg q8h AD iv
3TC/ABC   use individual drugs
3TC/ZDV
3TC/ABC/ZDV		   use individual drugs
d4T 30mg q12h 15mg q12h 15mg q24h 15mg q24h 15mg q24h AD iv
i eGFR: estimated glomerular filtration rate, according to the abbreviated MDRD formula (Modification of Diet in Renal disease)
ii dose reduction if combined with TDF
iii 150mg loading dose
iv AD: after dialysis